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It is quite unfair, then, to expect the physician to cure both sexes indifferently; we must recognize how far apart they are, their whole lives, pursuits, and habits, having been distinct from infancy. Do not talk of a mad person, then, but specify the sex; do not confound distinctions and force all cases under the supposed identical title of madness; keep separate what nature separates, and then examine the respective possibilities. I began this exposition with stating that the first thing we doctors look to is the nature and temperament of our patient’s body: which of the humours predominates in it; is it fullblooded or the reverse; at, or past, its prime; big or little; fat or lean? When a man has satisfied himself upon these and other such points, his opinion, favourable or adverse, upon the prospects of recovery may be implicitly relied upon.